Provitamin B 5 (Pantothenol) Inhibits Growth of the Intraerythrocytic Malaria Parasite

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Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite.

Pantothenic acid, a precursor of the crucial enzyme cofactor coenzyme A, is one of a relatively few nutrients for which the intraerythrocytic parasite has an absolute and acute requirement from the external medium. In some organisms the provitamin pantothenol can serve as a source of pantothenic acid; however, this was not the case for the human malaria parasite Plasmodium falciparum. Instead, ...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2005

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.49.2.632-637.2005